Senior Scientist Process Chemist

Full Job Description

Senior Scientist Process Chemist

Location: Dublin, Ireland

Date Open: 29th February 2024

Date Close: 17th March 2024

Introduction to the role:

Join our newly formed multi-skilled On-Market support group within the forefront Chemical Development labs at AstraZeneca’s new API manufacturing facility. As a senior scientist, you will play a crucial role in ensuring robust technology transfer, validation, and manufacturing to maintain continuity of supply and ensure license to operate. This role is a unique opportunity to shape the future of Operations at AstraZeneca and contribute to delivering more medicines to patients, quicker and more sustainably.

Accountabilities:

As a Senior Scientist, you will be responsible for supporting the technical contribution to transfer, maintain and optimise supply for one or more AstraZeneca commercial products. You will identify, develop and implement process improvements for both launch and commercial products through the use of existing and groundbreaking technologies. You will also provide expert technical input through laboratory experimentation, in-silico modelling and direct manufacturing support at our internal AZ API manufacturing site in Dublin. Your role will also involve providing a significant contribution to the CMC components of regulatory submissions and preparation of successful query responses over the commercial life of a product.

Essential Skills/Experience:

• BSc/PhD level education in a relevant subject area and experience working within a Research & Development or Manufacturing environment, within the pharmaceutical industry.

• Technical expertise and understanding of practical synthetic organic chemistry spanning across both lab and manufacture.

• Experience in the Tech Transfer of pharmaceutical Drug Substance processes

• Background in dealing with the challenges of both the scale-up and scale-down of processes

• A good understanding of the overall drug development process from discovery through to launch.

• A detailed understanding of the principles and management of SHE and cGMP.

• Excellent communication and strategic influencing skills across interfaces of discipline, culture, and expertise both internally and externally.

• Proven problem solver with in-depth technical skills.

• Proficiency in the use of statistics to understand data.

• Ability to think and operate across functional boundaries, challenge the status quo and seek opportunities for business improvement.

Desirable Skills/Experience:

• Experience in delivering CMC content or contributions to regulatory filings throughout the life cycle of process development, in the pharmaceutical industry.

• Experience working within a Research & Development and Manufacturing environment in the pharmaceutical industry

• Experience in technical supervision and leading small teams of people or scientific projects.

• Experience in late-stage development or commercial supply with a background in a process chemistry skill group

• Experience working across skillsets (e.g., with chemists, analysts and physical properties experts).

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we are driven by our commitment to deliver accelerated growth and to make people's lives better. It pushes us to keep building on our foundations and progressing as we turn our ever-growing and increasingly complex pipeline from molecule to medicine. Be part of evolving how we work with Lean, groundbreaking science, digitalisation and sustainable practices. We are a multigenerational workforce, open and respectful, we share to expand our minds and explore new areas. Curious problem-solvers, it is central to our purpose to keep digging, ask questions and achieve together.

Join the team where everyone feels a personal connection to the people that we impact. From our science labs to manufacturing at scale, we are committed to delivering at the highest quality. It's inspiring and rewarding work, influencing every part of the product lifecycle to deliver life-changing medicines. To ultimately make people's lives better. from patients and their families to all of us in society.

Ready to make a meaningful impact on people's lives with life-changing medicines? Apply now!

Date Posted

29-Feb-2024

Closing Date

16-Mar-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.